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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANAPC1
All Species:
8.48
Human Site:
T270
Identified Species:
16.97
UniProt:
Q9H1A4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A4
NP_073153.1
1944
216500
T270
Q
N
V
H
S
V
W
T
L
R
R
V
K
S
E
Chimpanzee
Pan troglodytes
XP_515601
1394
155989
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532958
1943
216470
A270
Q
S
L
H
S
V
W
A
L
R
R
V
K
T
E
Cat
Felis silvestris
Mouse
Mus musculus
P53995
1944
216068
T270
Q
N
V
H
S
V
W
T
L
R
R
V
K
P
E
Rat
Rattus norvegicus
NP_001101241
1944
216060
T270
Q
N
V
H
S
V
W
T
L
R
R
V
K
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419303
1945
216100
A271
Q
S
L
H
T
V
W
A
L
R
R
V
K
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921168
1979
220132
L270
C
T
H
T
V
W
N
L
R
K
V
T
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573025
2030
227256
P315
A
R
L
R
K
V
T
P
E
E
I
N
Y
V
S
Honey Bee
Apis mellifera
XP_001122449
1939
218025
K255
H
S
V
Y
K
I
R
K
A
S
I
E
E
C
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202400
910
100394
Poplar Tree
Populus trichocarpa
XP_002312165
1929
212815
K255
P
L
M
A
S
Y
N
K
G
K
M
Q
H
S
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196175
1678
186257
V72
F
I
R
D
N
C
N
V
R
K
G
Y
A
L
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
N.A.
97.3
N.A.
92.1
92.9
N.A.
N.A.
81.7
N.A.
66
N.A.
33.6
38
N.A.
25.2
Protein Similarity:
100
71.5
N.A.
98.5
N.A.
96
96.5
N.A.
N.A.
90.2
N.A.
79
N.A.
52.2
59.1
N.A.
33.8
P-Site Identity:
100
0
N.A.
73.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
0
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
13.3
N.A.
13.3
40
N.A.
0
Percent
Protein Identity:
28.5
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
47
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
17
9
0
0
0
9
0
0
% A
% Cys:
9
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
9
0
9
9
9
50
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% G
% His:
9
0
9
42
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
0
0
0
9
0
0
0
0
17
0
0
0
0
% I
% Lys:
0
0
0
0
17
0
0
17
0
25
0
0
42
0
0
% K
% Leu:
0
9
25
0
0
0
0
9
42
0
0
0
0
9
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
25
0
0
9
0
25
0
0
0
0
9
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
9
0
0
0
0
0
25
0
% P
% Gln:
42
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% Q
% Arg:
0
9
9
9
0
0
9
0
17
42
42
0
0
0
0
% R
% Ser:
0
25
0
0
42
0
0
0
0
9
0
0
9
17
9
% S
% Thr:
0
9
0
9
9
0
9
25
0
0
0
9
0
9
0
% T
% Val:
0
0
34
0
9
50
0
9
0
0
9
42
0
9
9
% V
% Trp:
0
0
0
0
0
9
42
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
9
0
0
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _